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Structure of 878285-12-2
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4-Chloro-2,3-difluoroaniline is a fluorinated aromatic amine featuring chlorine and two fluorine substituents in a strategic ortho/meta arrangement. This electron-deficient aniline derivative enables direct incorporation into pharmaceutical intermediates and agrochemical scaffolds, offering enhanced metabolic stability and tunable reactivity under standard coupling conditions.
4-Chloro-2,3-difluoroaniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling the construction of fluorinated heterocycles and bioactive scaffolds. Its ortho-difluoro substitution pattern enhances metabolic stability and modulates electronic properties, while the aniline functionality facilitates direct coupling reactions and electrophilic substitutions. The compound exhibits good bench stability and compatibility with standard purification methods, making it well-suited for iterative synthetic workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: