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Structure of 367-22-6
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4-Chloro-3-fluoroaniline features a strategically positioned chlorine and fluorine substituent on the aromatic ring, enabling precise tuning of electronic properties. This electron-deficient aniline derivative integrates readily into pharmaceutical intermediates and functional materials, offering enhanced reactivity in coupling processes under standard conditions.
4-Chloro-3-fluoroaniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to fluorinated aromatic scaffolds. Its ortho-halogenated aniline motif facilitates palladium-catalyzed cross-coupling reactions and provides enhanced metabolic stability in bioactive molecules. The compound exhibits good bench stability and compatibility with diverse functional groups, simplifying purification and downstream derivatization in multi-step syntheses.
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H311+H331-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: