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Structure of 885520-83-2
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4-Bromo-6-methoxy-1H-indazole is a heterocyclic building block featuring a bromine atom at the 4-position and a methoxy group at the 6-position on the indazole core. This combination imparts enhanced electron-withdrawing character and facilitates selective cross-coupling reactions under standard conditions. The molecule exhibits good bench stability and solubility in common organic solvents, enabling straightforward integration into synthetic sequences for pharmaceutical and materials research.
4-Bromo-6-methoxy-1H-indazole serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C4 position via palladium-catalyzed cross-coupling reactions. The methoxy group at C6 provides moderate electron-donating character and enhances solubility, while the indazole core offers metabolic stability and hydrogen-bonding capability. Bench-stable and readily purified by column chromatography, it facilitates efficient access to diverse heterocyclic scaffolds in API discovery campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: