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Structure of 886372-47-0
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4-Bromo-6-methylpicolinic acid features a strategically positioned bromine atom and methyl group on the picolinic acid scaffold, enabling direct functionalization in cross-coupling reactions. This electron-deficient heteroaromatic system delivers high reactivity in transition-metal-catalyzed transformations, particularly under standard conditions. The molecule exhibits excellent bench stability and solubility in common organic solvents, facilitating straightforward handling in synthetic workflows.
4-Bromo-6-methylpicolinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions. Its ortho-bromine and methyl-substituted pyridine core provide predictable reactivity for C–H functionalization and Suzuki-Miyaura coupling, with excellent bench stability and compatibility with common protecting group strategies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: