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Structure of 886767-49-3
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tert-Butyl 3-(4-chlorophenyl)piperazine-1-carboxylate features a piperazine core functionalized with a para-chlorophenyl group and a tert-butyl carbamate protecting group. This combination imparts excellent solubility in organic solvents and stability under standard bench conditions. The protected amine facilitates straightforward deprotection to access the free piperazine derivative, enabling efficient integration into pharmaceutical intermediates and bioactive molecule synthesis.
tert-Butyl 3-(4-chlorophenyl)piperazine-1-carboxylate serves as a stable, bench-ready building block for the synthesis of piperazine-based pharmaceuticals and bioactive molecules. The tert-butyl carbamate group enables facile deprotection under mild acidic conditions, while the 4-chlorophenyl substituent provides a versatile handle for palladium-catalyzed cross-coupling reactions. Its functional group tolerance and ease of purification make it ideal for iterative medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: