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CS-W001157 4
Total: USD 88.00

5-Bromo-1-methyl-1H-pyrazolo[3,4-b]pyridine

  • CAS No. 887115-56-2

  • Cat. No. CS-W000369
  • Purity≥98%
  • MDL No.MFCD16112604
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-1-methyl-1H-pyrazolo[3,4-b]pyridine|CS-W000369

Structure of 887115-56-2

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Description

5-Bromo-1-methyl-1H-pyrazolo[3,4-b]pyridine features a brominated pyrazolopyridine core with a methyl group at the 1-position, delivering a robust scaffold for medicinal chemistry. The electron-deficient heterocycle facilitates transition metal-catalyzed coupling reactions, while the bromide serves as a key handle for diversification. This bench-stable compound enables rapid access to complex nitrogen-rich architectures in drug discovery and materials science.

Application

5-Bromo-1-methyl-1H-pyrazolo[3,4-b]pyridine serves as a versatile building block for constructing biologically relevant heterocyclic scaffolds. Its bromine substituent enables efficient Pd-catalyzed cross-coupling reactions, while the methyl group enhances solubility and metabolic stability. The pyrazolopyridine core provides a rigid, planar framework suitable for targeted drug discovery applications. This compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry programs.

General Information

  • CAS No. 887115-56-2
  • Cat. No. CS-W000369
  • Purity ≥98%
  • MDL No. MFCD16112604
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrN₃
  • Molecular Weight 212.05
  • Synonym(s) None
  • SMILES Brc1cnc2c(c1)cnn2C

Computational Chemistry Data

  • TPSA   30.71
  • LogP   1.7308
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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