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Structure of 89323-09-1
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5-Aminopyrazine-2-carboxamide features a fused pyrazine core functionalized with amino and carboxamide groups at opposing positions, enabling versatile coordination in metal complexes and integration into bioactive heterocycles. This electron-rich scaffold supports hydrogen bonding and π-stacking interactions, enhancing solubility and molecular recognition in medicinal chemistry applications.
5-Aminopyrazine-2-carboxamide serves as a versatile heterocyclic building block in medicinal chemistry, enabling direct incorporation into bioactive scaffolds via amide coupling and cyclization reactions. Its dual functionality—amine and carboxamide groups—facilitates orthogonal derivatization, supports metal-catalyzed cross-couplings, and enhances solubility in polar reaction media. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step synthesis of kinase inhibitors and antitumor agents.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: