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CS-W001157 4
Total: USD 88.00

7-Bromo-2-chloroquinoxaline

  • CAS No. 89891-65-6

  • Cat. No. CS-W019688
  • Purity≥97%
  • MDL No.MFCD02955309
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

7-Bromo-2-chloroquinoxaline|CS-W019688

Structure of 89891-65-6

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Description

7-Bromo-2-chloroquinoxaline features a fused bicyclic core with complementary halogen substituents enabling selective cross-coupling reactions. The electron-deficient quinoxaline scaffold supports efficient palladium-catalyzed transformations, while the bromo and chloro groups offer orthogonal reactivity for sequential functionalization. This compound serves as a robust building block in synthetic pathways targeting bioactive heterocycles and advanced materials.

Application

7-Bromo-2-chloroquinoxaline serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The bromo group at the 7-position facilitates efficient Suzuki, Stille, or Negishi coupling, while the chloro group at the 2-position offers orthogonal reactivity for sequential functionalization. Its stability under standard reaction conditions and ease of purification make it ideal for constructing complex heterocyclic scaffolds in API development and advanced organic synthesis.

General Information

  • CAS No. 89891-65-6
  • Cat. No. CS-W019688
  • Purity ≥97%
  • MDL No. MFCD02955309
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄BrClN₂
  • Molecular Weight 243.49
  • Synonym(s) 2-chloro-7-bromo-quinoxaline
  • SMILES ClC1=NC2=CC(Br)=CC=C2N=C1

Computational Chemistry Data

  • TPSA   25.78
  • LogP   3.0457
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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