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Structure of 90390-07-1
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N-Methyl-1-(3-(trifluoromethyl)phenyl)methanamine features a trifluoromethyl group that imparts enhanced lipophilicity and metabolic stability. This electron-deficient aryl moiety enables efficient coupling in transition-metal-catalyzed transformations, while the N-methyl substitution ensures favorable solubility and reduced basicity. The compound serves as a robust scaffold for pharmaceutical intermediates and functional materials.
N-Methyl-1-(3-(trifluoromethyl)phenyl)methanamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard amine functionalization. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the N-methyl substitution improves solubility and reduces basicity. The compound exhibits bench-stable handling, tolerates diverse reaction conditions, and facilitates efficient coupling and derivatization in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1760
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H314-H412
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Precautionary Statements : P260-P264-P270-P273-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: