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Structure of 91526-18-0
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4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one is a bench-stable, moisture-tolerant synthon featuring a reactive α-hydroxycarbonyl moiety. This structure integrates readily into cascade cyclizations and C–C bond-forming sequences, enabling efficient access to functionalized heterocycles under mild conditions.
4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one serves as a versatile synthon in medicinal chemistry, enabling efficient access to functionalized heterocyclic scaffolds. Its α,β-unsaturated γ-lactone core facilitates Michael additions and nucleophilic transformations under mild conditions. The hydroxymethyl group provides a handle for further derivatization, while the molecule exhibits good bench stability and compatibility with common protecting group strategies. This compound functions effectively in multi-step synthesis workflows requiring controlled reactivity and predictable regioselectivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: