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tert-Butyl (trans-4-(2-hydroxyethyl)cyclohexyl)carbamate

  • CAS No. 917342-29-1

  • Cat. No. CS-0008599
  • Purity≥95%
  • MDL No.MFCD03844626

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (trans-4-(2-hydroxyethyl)cyclohexyl)carbamate|CS-0008599

Structure of 917342-29-1

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General Information

  • CAS No. 917342-29-1
  • Cat. No. CS-0008599
  • Purity ≥95%
  • MDL No. MFCD03844626
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₅NO₃
  • Molecular Weight 243.35
  • Synonym(s) None
  • SMILES N(C(OC(C)(C)C)=O)[C@H]1CC[C@H](CCO)CC1

Description

tert-Butyl (trans-4-(2-hydroxyethyl)cyclohexyl)carbamate features a rigid trans-cyclohexyl scaffold bearing a pendant hydroxyethyl side chain and a bench-stable tert-butyl carbamate protecting group. This configuration enables selective functionalization in peptide synthesis and complex molecule assembly, where steric control and solubility are critical.

Application

tert-Butyl (trans-4-(2-hydroxyethyl)cyclohexyl)carbamate serves as a versatile, bench-stable building block for cyclohexane-based scaffolds. The trans-configured cyclohexyl core provides defined stereochemistry, while the pendant hydroxyl group enables downstream derivatization via esterification, etherification, or oxidation. The Boc-protected amine offers orthogonal functionality, facilitating selective transformations in complex molecule synthesis. Its stability and ease of purification make it well-suited for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   2.4523
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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