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Structure of 921599-70-4
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2,2-Difluorocyclopentan-1-amine hydrochloride features a rigid cyclopentane core with two fluorine atoms at the geminal position, imparting enhanced metabolic stability and lipophilicity. This bench-stable salt form improves solubility and handling in synthetic workflows, enabling efficient incorporation into bioactive molecules for medicinal chemistry applications.
2,2-Difluorocyclopentan-1-amine hydrochloride serves as a conformationally constrained building block for medicinal chemistry, enabling the introduction of fluorinated cyclopentane motifs into bioactive molecules. The difluoro substitution enhances metabolic stability and modulates lipophilicity, while the amine functionality facilitates facile derivatization via alkylation, acylation, or coupling reactions. Bench-stable and readily purified, it functions effectively in standard synthetic workflows targeting CNS agents and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: