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Structure of 92367-11-8
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This diazirine derivative features a bromomethyl group flanking a trifluoromethyl-substituted aromatic ring, enabling efficient photoaffinity labeling. The electron-deficient diazirine moiety integrates readily into bioconjugation workflows under standard conditions.
3-(4-(Bromomethyl)phenyl)-3-(trifluoromethyl)-3H-diazirine serves as a versatile photoaffinity labeling probe, enabling site-specific protein crosslinking upon UV irradiation. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the bromomethyl moiety facilitates downstream conjugation via nucleophilic substitution. Its bench-stable crystalline form and compatibility with standard synthetic workflows make it ideal for probing biomolecular interactions in drug discovery and chemical biology applications.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 2924
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Class : 3,8
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Packing Group : Ⅱ
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Hazard Statements : H226-H314
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: