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CS-W001157 4
Total: USD 88.00

Methyl 2-amino-5-fluoro-4-methylbenzoate

  • CAS No. 929214-84-6

  • Cat. No. CS-0061801
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 2-amino-5-fluoro-4-methylbenzoate|CS-0061801

Structure of 929214-84-6

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General Information

  • CAS No. 929214-84-6
  • Cat. No. CS-0061801
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀FNO₂
  • Molecular Weight 183.18
  • Synonym(s) METHYL 2-AMINO-5-FLUORO-4-METHYLBENZOATE(WS201337)
  • SMILES COC(=O)C=1C=C(F)C(C)=CC1N

Description

Methyl 2-amino-5-fluoro-4-methylbenzoate features a strategically positioned amino group flanked by fluorine and methyl substituents, enabling precise tuning of electronic properties. This electron-rich scaffold integrates readily into pharmaceutical intermediates, offering enhanced solubility and stability under standard conditions. The functionalized aromatic core supports efficient coupling reactions, streamlining access to complex heterocyclic architectures in medicinal chemistry.

Application

Methyl 2-amino-5-fluoro-4-methylbenzoate serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted benzimidazoles and other heterocyclic scaffolds. Its ortho-amino and meta-fluoro functionalities facilitate directed metalation and subsequent coupling reactions, while the methyl ester group allows for selective derivatization. The compound exhibits good bench stability and is compatible with standard synthetic workflows, supporting scalable synthesis of bioactive intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.50292
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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