Propargyl-PEG3-amine

Name: Propargyl-PEG3-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 932741-19-0
Cat. No. CS-0114325
Purity≥96%
MDL No.MFCD20720810

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Structure of 932741-19-0

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Description

Propargyl-PEG3-amine is a bifunctional linker featuring a terminal alkyne for click chemistry and a primary amine for conjugation. This water-soluble, bench-stable reagent integrates seamlessly into bioconjugation workflows, enabling efficient coupling via copper-catalyzed or strain-promoted azide-alkyne cycloaddition.

Application

Propargyl-PEG3-amine serves as a versatile bifunctional linker for bioconjugation and polymer chemistry, combining the reactive terminal alkyne with a stable, hydrophilic PEG3 spacer. It enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for site-specific conjugation, while the amine group facilitates coupling to carboxylate or activated ester functionalities. Its excellent solubility, bench stability, and ease of purification make it ideal for synthesizing peptide-PEG-protein conjugates, drug delivery systems, and functionalized surfaces in high-throughput workflows.

General Information

CAS No. 932741-19-0
Cat. No. CS-0114325
Purity ≥96%
MDL No. MFCD20720810
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₇NO₃
Molecular Weight 187.24
Synonym(s) None
SMILES C#CCOCCOCCOCCN

Computational Chemistry Data

TPSA 53.71
LogP -0.3719
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 9

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Other Classifications

Building Blocks Functional Group PEG

Building Blocks Skeleton Fatty chain compounds

Life Science Linker Alkyne PEG

Life Science Linker Propargyl PEG

Life Science Click Chemistry Reagents

Chemical Biology Pharmaceutical Development and Drug Discovery Research Conjugation Chemistry/Click Chemistry Amino Acid Azides/Alkynes

Chemical Biology Pharmaceutical Development and Drug Discovery Research Conjugation Chemistry/Click Chemistry PEG Azides/Alkynes

Chemical Biology Conjugation Chemistry/Click Chemistry Amino Acid Azides/Alkynes

Chemical Biology Conjugation Chemistry/Click Chemistry PEG Azides/Alkynes

Chemical Biology PEGylation Monofunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation Heterobifunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation PEG Oligomers

Biochemistry Biochemicals and Reagents Bioconjugation PEGylation Reagents and PEG Spacers

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Propargyl-PEG3-amine

CAS No. 932741-19-0

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