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Structure of 934664-41-2
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tert-Butyl 3-methyleneazetidine-1-carboxylate features a strained azetidine ring with an exocyclic methylene group, enabling direct functionalization at the 3-position. This reactive scaffold integrates readily into diverse synthetic sequences, offering efficient access to nitrogen-containing heterocycles under mild conditions. The tert-butyl ester provides stability and ease of manipulation during multi-step transformations.
tert-Butyl 3-methyleneazetidine-1-carboxylate serves as a versatile, bench-stable building block for the synthesis of strained azetidine scaffolds. Its exocyclic methylene group enables efficient [2+2] cycloadditions and Michael-type additions, facilitating access to functionalized nitrogen heterocycles. The tert-butyl ester provides excellent solubility and compatibility with standard purification methods, while the azetidine core offers high reactivity in late-stage functionalization workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: