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Structure of 934758-27-7
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2-Amino-6-bromopyridin-3-ol features a bromine substituent at the 6-position and a hydroxyl group at the 3-position of the pyridine core, enabling direct functionalization in cross-coupling reactions. The amino group enhances nucleophilicity, while the electron-deficient ring facilitates palladium-catalyzed transformations. This scaffold offers high reactivity under standard conditions and demonstrates stability during handling.
2-Amino-6-bromopyridin-3-ol serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted pyridine scaffolds via Pd-catalyzed cross-coupling and electrophilic substitution reactions. Its dual amino and hydroxyl functionalities offer orthogonal reactivity for sequential derivatization, while the bromine atom provides a reliable handle for C–C bond formation. The compound exhibits good bench stability and is readily purified by recrystallization, facilitating its use in high-throughput synthesis of API candidates and functionalized heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: