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CS-W001157 4
Total: USD 88.00

(R)-3-Aminotetrahydrothiophene 1,1-dioxide hydrochloride

  • CAS No. 935455-27-9

  • Cat. No. CS-B0948
  • Purity≥98%
  • MDL No.MFCD22418841

*For research and further manufacturing use only, not for direct human use.

(R)-3-Aminotetrahydrothiophene 1,1-dioxide hydrochloride|CS-B0948

Structure of 935455-27-9

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General Information

  • CAS No. 935455-27-9
  • Cat. No. CS-B0948
  • Purity ≥98%
  • MDL No. MFCD22418841
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀ClNO₂S
  • Molecular Weight 171.65
  • Synonym(s) None
  • SMILES N[C@H](CC1)CS1(=O)=O.[H]Cl

Description

(R)-3-Aminotetrahydrothiophene 1,1-dioxide hydrochloride is a chiral sulfonamide derivative featuring a rigid tetrahydrothiophene core with high stereochemical integrity. The protonated amine enhances solubility in aqueous media while the sulfone group imparts exceptional metabolic stability and polarity. This compound serves as a key building block in medicinal chemistry for targeted incorporation into bioactive molecules requiring defined spatial orientation and enhanced pharmacokinetic profiles.

Application

(R)-3-Aminotetrahydrothiophene 1,1-dioxide hydrochloride serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of sulfonamide-containing heterocycles and bioactive molecules. Its well-defined stereochemistry and bench-stable hydrochloride salt form facilitate straightforward handling, purification, and incorporation into diverse synthetic sequences. The molecule functions as a versatile scaffold for constructing pharmaceutically relevant motifs through standard amine functionalization and coupling reactions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   60.16
  • LogP   -0.446
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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