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Structure of 939968-08-8
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2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline delivers a sterically protected boronate handle flanked by two electron-withdrawing fluorine atoms. This bench-stable reagent integrates readily into Suzuki-Miyaura coupling protocols, enabling efficient C–C bond formation under mild conditions. The para-boronate moiety enhances reactivity while the difluorinated aryl framework provides orthogonal stability and tunable electronic properties.
2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The difluoro substitution pattern enhances metabolic stability and modulates electronic properties, while the pinacol boronate group ensures excellent bench stability and compatibility with diverse reaction conditions. This reagent facilitates efficient construction of biaryl scaffolds in medicinal chemistry and materials science, offering reliable coupling yields and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: