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Structure of 819058-34-9
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2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline features a boronate ester group enabling efficient Suzuki-Miyaura coupling under mild conditions. The fluorine substituent imparts electronic modulation and enhanced metabolic stability. This bench-stable reagent integrates readily into complex molecule synthesis, offering predictable reactivity and high functional group tolerance in pharmaceutical and agrochemical applications.
2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The ortho-fluoro substituent enables directed ortho-metalation and facilitates downstream functionalization, while the pinacol boronate group offers excellent stability, ease of handling, and compatibility with a broad range of coupling partners. This compound functions reliably in the construction of biaryl scaffolds relevant to medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: