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7-Bromo-3-iodo-1H-indazole

  • CAS No. 944904-26-1

  • Cat. No. CS-0050084
  • Molecule weight322.93
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Bromo-3-iodo-1H-indazole|CS-0050084

Structure of 944904-26-1

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General Information

  • CAS No. 944904-26-1
  • Cat. No. CS-0050084
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrIN₂
  • Molecular Weight 322.93
  • Synonym(s) 7-Bromo-3-iodoindazole
  • SMILES BrC1=CC=CC2=C1NN=C2I

Description

7-Bromo-3-iodo-1H-indazole is a halogenated indazole scaffold featuring complementary reactive sites for cross-coupling applications. The bromine at the 7-position and iodine at the 3-position enable sequential functionalization under palladium catalysis. This electron-deficient heterocycle offers enhanced stability and predictable reactivity in C–C bond formation, making it ideal for constructing complex molecular architectures in medicinal chemistry and materials science.

Application

7-Bromo-3-iodo-1H-indazole serves as a versatile bifunctional building block for palladium-catalyzed cross-coupling reactions. The bromo and iodo substituents enable sequential functionalization, facilitating the construction of complex indazole scaffolds with high regiocontrol. Its bench-stable nature and compatibility with standard coupling conditions make it well-suited for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.93
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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