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Structure of 947533-94-0
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This boronate reagent features a sterically accessible aryl group with a trifluoromethyl substituent, enhancing electronic effects and stability. It integrates efficiently into Suzuki-Miyaura cross-coupling reactions under standard conditions, delivering robust yields with minimal protodeboronation.
(4-Methyl-3-(trifluoromethyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. Its trifluoromethyl and methyl substituents enhance metabolic stability and modulate electronic properties, making it particularly valuable for medicinal chemistry applications. The boronic acid functionality offers excellent bench stability, tolerates common functional groups, and facilitates straightforward purification—key attributes for scalable synthesis and high-throughput screening workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: