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Structure of 94940-35-9
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Bis(4-fluorophenyl)phosphine oxide features a phosphine oxide core flanked by electron-deficient fluorophenyl groups, enhancing stability and resistance to oxidation. This bench-stable reagent integrates readily into palladium-catalyzed cross-coupling reactions, offering predictable coordination geometry and improved solubility in organic media.
Bis(4-fluorophenyl)phosphine oxide serves as a stable, bench-ready ligand in palladium-catalyzed cross-coupling reactions. Its electron-withdrawing fluorophenyl groups enhance oxidative addition kinetics while maintaining compatibility with diverse functional groups. The phosphine oxide functionality provides improved air stability and simplifies purification, making it well-suited for reproducible, scalable synthesis of biaryl architectures in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: