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Structure of 954219-68-2
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2,3-Difluoro-5-nitropyridine features a highly electron-deficient pyridine core, enabling efficient coupling in cross-coupling reactions. The ortho-fluorine substituents facilitate selective functionalization, while the para-nitro group serves as a potent acceptor for nucleophilic substitution. This compound integrates seamlessly into complex heterocyclic architectures under standard conditions.
2,3-Difluoro-5-nitropyridine serves as a versatile building block in medicinal chemistry, enabling site-selective functionalization via nucleophilic substitution at the C3 position. Its electron-deficient pyridine core facilitates cross-coupling reactions and acts as a key scaffold for constructing bioactive heterocycles. The molecule exhibits good bench stability and compatibility with standard purification methods, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: