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Structure of 954236-44-3
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tert-Butyl 3-oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylate features a spirocyclic scaffold with embedded oxygen and nitrogen heteroatoms, delivering structural rigidity and defined stereochemistry. The tert-butyl ester group enables stable handling and convenient deprotection under mild acidic conditions. This compound serves as a key building block for complex heterocyclic architectures in medicinal chemistry and natural product synthesis.
tert-Butyl 3-oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylate serves as a versatile spirocyclic building block for medicinal chemistry and natural product synthesis. Its structure integrates a ketone, a tertiary amine, and a stable tert-butyl ester, enabling selective functionalization and orthogonal transformations. The spirocyclic core provides rigidity and defined stereochemistry, facilitating efficient access to complex heterocyclic scaffolds via reductive amination, conjugate addition, or cyclization reactions. Ideal for iterative synthesis workflows due to its bench stability and ease of purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: