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Structure of 98426-27-8
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4-(Dimethylamino)-4-methyl-2-pentynoic acid features a conjugated alkyne-carboxylic acid motif paired with a tertiary dimethylamino group, enabling efficient coupling in click chemistry. The electron-donating amine enhances reactivity in copper-catalyzed azide-alkyne cycloaddition, while the methyl substituent provides steric stabilization. This compound integrates readily into bioconjugation workflows and functional material synthesis under standard conditions.
4-(Dimethylamino)-4-methyl-2-pentynoic acid serves as a versatile building block for synthesizing α,β-unsaturated carbonyl systems and heterocyclic scaffolds via [3+2] cycloadditions or nucleophilic additions. The conjugated alkyne–carboxylic acid motif enables reliable coupling reactions, while the dimethylamino group enhances electrophilic reactivity. Bench-stable and amenable to standard purification methods, it functions effectively in multistep syntheses requiring functional group tolerance and predictable regiochemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: