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Structure of 99207-32-6
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tert-Butyl (4-hydroxybutyl)(methyl)carbamate features a hydroxyl-bearing aliphatic chain linked to a carbamate group, enabling selective protection and functionalization in peptide synthesis. The tert-butyl moiety provides acid-labile stability, while the pendant hydroxyl facilitates downstream derivatization or conjugation under mild conditions. This structure combines orthogonal handle compatibility with robust bench stability and ease of handling.
tert-Butyl (4-hydroxybutyl)(methyl)carbamate serves as a versatile protected hydroxyl building block in synthetic organic chemistry, enabling straightforward access to functionalized aliphatic chains. The tert-butoxycarbonyl (Boc) group provides excellent bench stability and orthogonal deprotection under mild acidic conditions, while the primary alcohol facilitates subsequent derivatization via esterification, ether formation, or oxidation. Its methyl carbamate functionality enhances solubility and compatibility in polar reaction media, making it well-suited for peptide analogs, macrocyclic scaffolds, and medicinal chemistry lead optimization.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: