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Structure of 99420-75-4
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5-Methylpyrimidine-2-carboxylic acid features a pyrimidine core bearing a methyl group at the 5-position and a carboxylic acid at the 2-position, enabling direct integration into heterocyclic scaffolds. This electron-deficient motif facilitates coupling reactions under mild conditions, offering a robust platform for medicinal chemistry campaigns targeting kinase inhibitors and other bioactive molecules.
5-Methylpyrimidine-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrimidine-based scaffolds prevalent in kinase inhibitors and antiviral agents. Its carboxylic acid functionality facilitates amide coupling and esterification, while the methyl group enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability and compatibility with standard functional group manipulations, making it ideal for modular synthesis and high-throughput screening campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: