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Structure of 99974-66-0
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Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate features a strained cyclobutane core with a hydroxyl group and two ester functionalities, enabling direct functionalization at the C3 position. The geminal diester motif enhances reactivity in nucleophilic transformations, while the hydroxyl group provides a handle for derivatization. This scaffold supports efficient access to substituted cyclobutanes under mild conditions.
Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate serves as a versatile building block in synthetic organic chemistry, enabling the construction of cyclobutane-containing scaffolds through standard functional group manipulations. The hydroxyl group facilitates derivatization via esterification, oxidation, or protection, while the geminal diester functionality supports selective transformations and ring functionalization. Its bench-stable nature and compatibility with common coupling and reduction protocols make it valuable for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: