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Structure of 1352796-65-6
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2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine delivers a boronate handle ortho to a fluoropyrimidine core, enabling direct coupling in palladium-catalyzed cross-coupling reactions. The tetramethylboronate moiety enhances stability and reactivity under standard conditions, while the electron-deficient pyrimidine ring supports efficient functionalization. This compound serves as a key building block for medicinal chemistry and materials science applications.
2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine serves as a versatile boronate building block for palladium-catalyzed cross-coupling reactions. The pyrimidine core provides a stable heterocyclic scaffold with defined regiochemistry, while the pinacol boronate group enables efficient coupling under mild conditions. Its bench stability and compatibility with diverse functional groups make it ideal for constructing complex molecular architectures in medicinal chemistry and materials science workflows.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P405-P501
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Lot numbers can be found on the outside label of a product: