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tert-Butyl N-[(1-aminocyclohexyl)methyl]carbamate

  • CAS No. 1352999-04-2

  • Cat. No. CS-0048048
  • Molecule weight228.33
  • Purity≥97%
  • MDL No.MFCD21091404

*For research and further manufacturing use only, not for direct human use.

tert-Butyl N-[(1-aminocyclohexyl)methyl]carbamate|CS-0048048

Structure of 1352999-04-2

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General Information

  • CAS No. 1352999-04-2
  • Cat. No. CS-0048048
  • Purity ≥97%
  • MDL No. MFCD21091404
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₄N₂O₂
  • Molecular Weight 228.33
  • Synonym(s) tert-butyl ((1-aMinocyclohexyl)Methyl)carbaMate
  • SMILES CC(C)(C)OC(=O)NCC1(N)CCCCC1

Description

tert-Butyl N-[(1-aminocyclohexyl)methyl]carbamate delivers a protected amine handle with enhanced solubility and stability in aqueous and organic media. This bench-stable derivative features a cyclohexylmethyl-amino scaffold ideal for peptide coupling and bioconjugation workflows. The tert-butyl carbamate group enables orthogonal deprotection under mild acidic conditions, streamlining synthesis of functionalized intermediates.

Application

tert-Butyl N-[(1-aminocyclohexyl)methyl]carbamate serves as a stable, bench-friendly amino protecting group for cyclohexylamine derivatives. It facilitates straightforward deprotection under mild acidic conditions and exhibits excellent functional group tolerance in multistep syntheses. The carbamate moiety enables selective coupling reactions and supports the construction of complex heterocyclic scaffolds and bioactive molecules in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   2.1727
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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