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Structure of 1519318-68-3
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4-Bromoisoxazol-3-amine features a brominated isoxazole core with a pendant amine group, enabling direct incorporation into diverse heterocyclic scaffolds. This bench-stable, moisture-tolerant building block facilitates efficient access to bioactive compounds through cross-coupling and cyclization strategies.
4-Bromoisoxazol-3-amine serves as a versatile building block in medicinal chemistry, enabling the construction of isoxazole-based scaffolds through palladium-catalyzed cross-coupling reactions. Its bromine handle facilitates efficient functionalization via Suzuki, Stille, or Negishi transformations, while the pendant amine group offers orthogonal reactivity for derivatization. The compound exhibits good bench stability and compatibility with standard purification methods, making it well-suited for iterative synthesis campaigns targeting bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: