tert-Butyl 5-oxo-5,6-dihydropyridine-1(2H)-carboxylate

CAS No. 156496-89-8
Cat. No. CS-0006476
Purity≥97%
MDL No.MFCD22394907

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 5-oxo-5,6-dihydropyridine-1(2H)-carboxylate|CS-0006476

Structure of 156496-89-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

tert-Butyl 5-oxo-5,6-dihydropyridine-1(2H)-carboxylate is a bench-stable, moisture-tolerant heterocyclic building block featuring a conjugated enone system. This scaffold integrates seamlessly into synthetic routes targeting nitrogen-containing pharmaceutical intermediates, where the electrophilic carbonyl and dihydropyridine ring enable selective functionalization under mild conditions.

Application

tert-Butyl 5-oxo-5,6-dihydropyridine-1(2H)-carboxylate serves as a versatile building block for pyridine-based heterocycles, enabling efficient access to substituted dihydropyridines via reductive amination or conjugate addition. The tert-butyl ester group provides excellent bench stability and facilitates straightforward deprotection under mild acidic conditions. Its dual functionality—olefinic C=C bond and carbonyl group—supports diverse transformations, including hydrogenation, nucleophilic addition, and coupling reactions, making it well-suited for medicinal chemistry campaigns targeting bioactive scaffolds.

General Information

CAS No. 156496-89-8
Cat. No. CS-0006476
Purity ≥97%
MDL No. MFCD22394907
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₅NO₃
Molecular Weight 197.23
Synonym(s) tert-Butyl 3-oxo-3,6-dihydropyridine-1(2H)-carboxylate
SMILES O=C(N1CC=CC(C1)=O)OC(C)(C)C

Computational Chemistry Data

TPSA 46.61
LogP 1.3624
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Other aliphatic heterocycles compounds

Key Words

156496-89-8 sigma156496-89-8 manufacturer156496-89-8 price156496-89-8 structure156496-89-8 SDSbuy 156496-89-8156496-89-8 supplier156496-89-8 uses156496-89-8 molecular weightprice of 156496-89-8156496-89-8 chemical name formula of 156496-89-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl 5-oxo-5,6-dihydropyridine-1(2H)-carboxylate

CAS No. 156496-89-8

Recommended Products