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CS-W001157 4
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tert-Butyl (S)-4-amino-2-((tert-butoxycarbonyl)amino)butanoate

  • CAS No. 190447-69-9

  • Cat. No. CS-0255059
  • Molecule weight274.36
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (S)-4-amino-2-((tert-butoxycarbonyl)amino)butanoate|CS-0255059

Structure of 190447-69-9

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General Information

  • CAS No. 190447-69-9
  • Cat. No. CS-0255059
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₆N₂O₄
  • Molecular Weight 274.36
  • Synonym(s) tert-butyl (2S)-4-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoate
  • SMILES O=C(OC(C)(C)C)[C@@H](NC(OC(C)(C)C)=O)CCN

Description

tert-Butyl (S)-4-amino-2-((tert-butoxycarbonyl)amino)butanoate features a chiral backbone with orthogonal protection: the amine at C4 is free, while the α-amino group bears a tert-butoxycarbonyl (Boc) handle. This configuration enables selective derivatization during peptide synthesis or functionalization of bioactive scaffolds, where the unprotected amino group participates in coupling reactions under standard conditions. The molecule exhibits stability under bench handling and tolerates common deprotection protocols.

Synthesis

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    • In-stock
      tert-Butyl (S)-4-amino-2-((tert-butoxycarbonyl)amino)butanoate|CS-0255059
      190447-69-9

    References

    • Xue, Chu-Biao; Wityak, John; Sielecki, Thais M.; Pinto, Donald J.; Batt, Douglas G.; Cain, Gary A.; Sworin, Michael; Rockwell, Arlene L.; Roderick, John J.; Wang, Shuaige; Orwat, Michael J.; Frietze, William E.; Bostrom, Lori L.; Liu, Jie; Higley, C. Anne; Rankin, F. Wayne; Tobin, A. Ewa; Emmett, George; Lalka, George K.; Sze, Jean Y.; Di Meo, Susan V.; Mousa, Shaker A.; Thoolen, Martin J.; Racanelli, Adrienne L.; Hausner, Elizabeth A.; Reilly, Thomas M.; DeGrado, William F.; Wexler, Ruth R.; Olson, Richard E. Journal of Medicinal Chemistry, 1997 , vol. 40, # 13 p. 2064 - 2084
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    References

    • Custot; Moali; Brollo; Boucher; Delaforge; Mansuy; Tenu; Zimmermann Journal of the American Chemical Society, 1997 , vol. 119, # 17 p. 4086 - 4087
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    References

    • Custot; Moali; Brollo; Boucher; Delaforge; Mansuy; Tenu; Zimmermann Journal of the American Chemical Society, 1997 , vol. 119, # 17 p. 4086 - 4087

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   90.65
  • LogP   1.5702
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   4

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