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Structure of 191348-14-8
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2-Iodo-4-methoxyaniline serves as a key intermediate in the synthesis of functionalized aromatic systems, featuring a reactive iodine handle and a methoxy group that enhances electron density. This combination enables efficient coupling reactions under mild conditions, particularly in palladium-catalyzed cross-couplings. The compound exhibits good stability and solubility in common organic solvents, facilitating straightforward handling in process development workflows.
2-Iodo-4-methoxyaniline serves as a versatile building block in cross-coupling reactions, enabling efficient access to substituted anilines and biaryl scaffolds. Its iodine functionality provides high reactivity in Pd-catalyzed couplings, while the methoxy group offers moderate electron-donating character and stability under standard reaction conditions. The compound exhibits good bench stability and is readily purified by chromatography or recrystallization, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS No : GHS07,GHS08
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335-H351-H361
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: