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Structure of 2835-97-4
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2-Amino-3-methylphenol serves as a key intermediate in pharmaceutical synthesis, featuring a strategically positioned amino group adjacent to a phenolic hydroxyl. This arrangement enables facile coupling reactions and facilitates incorporation into bioactive scaffolds. The methyl substituent enhances metabolic stability while maintaining favorable reactivity profiles under standard conditions.
2-Amino-3-methylphenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling access to substituted heterocycles via cyclization and coupling reactions. Its ortho-diamine motif facilitates metal-catalyzed cross-coupling and oxidative aromatization, while the methyl group enhances metabolic stability. The compound exhibits good bench stability and is readily purified by crystallization or column chromatography, supporting its use in multi-step synthetic sequences requiring functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352
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Lot numbers can be found on the outside label of a product: