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Structure of 2869955-58-6
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5-Hydroxy-6-methylpyrimidine-4-carboxylic acid features a pyrimidine core bearing a hydroxyl group at C5, a methyl substituent at C6, and a carboxylic acid at C4. This arrangement delivers a polar, electron-deficient scaffold suitable for bioconjugation and medicinal chemistry applications. The molecule exhibits bench-stable handling characteristics and integrates readily into diverse synthetic pathways.
5-Hydroxy-6-methylpyrimidine-4-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling access to pyrimidine-based scaffolds prevalent in medicinal chemistry. Its orthogonal functional groups—phenolic hydroxyl, methyl, and carboxylic acid—facilitate diverse transformations including amidation, esterification, and metal-catalyzed coupling reactions. The compound exhibits good bench stability and is amenable to purification via recrystallization or chromatography, supporting its use in iterative synthetic sequences and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: