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CS-W001157 4
Total: USD 88.00

5-Hydroxy-6-methylpyrimidine-4-carboxylic acid

  • CAS No. 2869955-58-6

  • Cat. No. CS-0634592
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Hydroxy-6-methylpyrimidine-4-carboxylic acid|CS-0634592

Structure of 2869955-58-6

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Description

5-Hydroxy-6-methylpyrimidine-4-carboxylic acid features a pyrimidine core bearing a hydroxyl group at C5, a methyl substituent at C6, and a carboxylic acid at C4. This arrangement delivers a polar, electron-deficient scaffold suitable for bioconjugation and medicinal chemistry applications. The molecule exhibits bench-stable handling characteristics and integrates readily into diverse synthetic pathways.

Application

5-Hydroxy-6-methylpyrimidine-4-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling access to pyrimidine-based scaffolds prevalent in medicinal chemistry. Its orthogonal functional groups—phenolic hydroxyl, methyl, and carboxylic acid—facilitate diverse transformations including amidation, esterification, and metal-catalyzed coupling reactions. The compound exhibits good bench stability and is amenable to purification via recrystallization or chromatography, supporting its use in iterative synthetic sequences and API intermediate development.

General Information

  • CAS No. 2869955-58-6
  • Cat. No. CS-0634592
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆N₂O₃
  • Molecular Weight 154.12
  • Synonym(s) None
  • SMILES O=C(C1=NC=NC(C)=C1O)O

Computational Chemistry Data

  • TPSA   83.31
  • LogP   0.18882
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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