6-Bromo-3-methylpyridin-2-amine

CAS No. 89466-16-0
Cat. No. CS-W007289
Purity≥98%
MDL No.MFCD17014961

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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6-Bromo-3-methylpyridin-2-amine|CS-W007289

Structure of 89466-16-0

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Description

6-Bromo-3-methylpyridin-2-amine features a bromine atom at the 6-position and a methyl group at the 3-position on a pyridine ring bearing an amino functionality at the 2-position. This electron-deficient heterocycle integrates readily into cross-coupling reactions, enabling efficient access to functionalized pyridine scaffolds in medicinal chemistry and materials science.

Application

6-Bromo-3-methylpyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromine substituent. The pyridin-2-amine core provides a handle for further functionalization, while the methyl group enhances metabolic stability. Its bench-stable nature and compatibility with standard synthetic protocols facilitate efficient assembly of heterocyclic scaffolds in API development.

General Information

CAS No. 89466-16-0
Cat. No. CS-W007289
Purity ≥98%
MDL No. MFCD17014961
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇BrN₂
Molecular Weight 187.04
Synonym(s) 6-BroMo-3-Methyl-2-pyridinaMine
SMILES NC1=NC(Br)=CC=C1C

Computational Chemistry Data

TPSA 38.91
LogP 1.73472
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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6-Bromo-3-methylpyridin-2-amine

CAS No. 89466-16-0

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