6-Bromo-5-methylpyridin-2-amine

Name: 6-Bromo-5-methylpyridin-2-amine
Brand: ChemScene
Availability: InStock
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CAS No. 89466-17-1
Cat. No. CS-0050259
Purity≥97%
MDL No.MFCD20704687

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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6-Bromo-5-methylpyridin-2-amine|CS-0050259

Structure of 89466-17-1

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Description

6-Bromo-5-methylpyridin-2-amine features a bromine atom at the 6-position and a methyl group at the 5-position on a pyridine scaffold bearing an amino function at C2. This electron-deficient heterocycle integrates readily into cross-coupling reactions, enabling efficient construction of complex nitrogen-containing architectures in medicinal chemistry and materials science.

Application

6-Bromo-5-methylpyridin-2-amine serves as a versatile building block for medicinal chemistry and heterocyclic synthesis. The bromine at C6 enables palladium-catalyzed cross-coupling reactions, while the pyridin-2-amine functionality facilitates direct functionalization or metal coordination. Its methyl group enhances lipophilicity and metabolic stability in drug-like scaffolds. This compound exhibits bench stability, tolerates diverse reaction conditions, and is compatible with standard purification methods, making it ideal for constructing complex nitrogen-containing architectures in API development.

General Information

CAS No. 89466-17-1
Cat. No. CS-0050259
Purity ≥97%
MDL No. MFCD20704687
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇BrN₂
Molecular Weight 187.04
Synonym(s) 6-Bromo-5-methylpyridin-2-amine(For export only)
SMILES NC1=NC(Br)=C(C)C=C1

Computational Chemistry Data

TPSA 38.91
LogP 1.73472
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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6-Bromo-5-methylpyridin-2-amine

CAS No. 89466-17-1

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