4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine

CAS No. 943323-55-5
Cat. No. CS-B0565
Purity≥95%
MDL No.MFCD12962664

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine|CS-B0565

Structure of 943323-55-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 943323-55-5
Cat. No. CS-B0565
Purity ≥95%
MDL No. MFCD12962664
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆BrN₃
Molecular Weight 212.05
Synonym(s) 1H-Pyrrolo[2,3-b]pyridin-6-aMine, 4-broMo-
SMILES BrC1=C2C(NC=C2)=NC(N)=C1

Description

4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine features a brominated pyrrolopyridine core with a pendant amine group, enabling direct functionalization in C–N cross-coupling reactions. The electron-deficient heteroaromatic scaffold supports palladium-catalyzed transformations, while the amine moiety serves as a handle for derivatization. This compound offers high reactivity and bench stability under standard conditions.

Application

4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromo-substituted heterocyclic core. The pyrrolo[2,3-b]pyridine scaffold provides enhanced metabolic stability and favorable pharmacophore properties, while the primary amine functionality supports direct derivatization or conjugation. Bench-stable and readily purified, it facilitates efficient synthesis of complex nitrogen-containing scaffolds for drug discovery applications.

Synthesis

Route1
- 640735-27-9
- ~36%
- In-stock
  
  943323-55-5
References
- SMITHKLINE BEECHAM CORPORATION Patent: WO2007/76423 A2, 2007 ; Location in patent: Page/Page column 151 ; WO 2007/076423 A2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 54.7
LogP 1.9076
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Key Words

4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine sigma4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine manufacturer4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine price4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine structure4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine SDSbuy 4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine supplier4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine uses4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine molecular weightprice of 4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine chemical name formula of 4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Bromo-1H-pyrrolo[2,3-b]pyridin-6-amine

CAS No. 943323-55-5

Recommended Products