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Structure of 1007110-53-3
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1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole delivers a stable, moisture-tolerant boronate handle for efficient Suzuki-Miyaura coupling. This bench-stable reagent integrates readily into complex molecular architectures, enabling rapid access to functionalized pyrazole scaffolds under standard conditions.
1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The pyrazole core provides metabolic stability and tunable polarity, while the pinacol boronate group offers excellent bench stability, mild reaction conditions, and broad functional group tolerance. This reagent facilitates efficient C–C bond formation in the synthesis of biaryl and heteroaryl scaffolds relevant to medicinal chemistry and materials science.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: