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Structure of 1018678-38-0
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4-Amino-2-chloropyridine-3-carboxylic acid features a conjugated pyridine core bearing electron-donating amino and electron-withdrawing chloro and carboxylic acid groups, enabling versatile integration into pharmaceutical scaffolds. This arrangement supports hydrogen bonding and dipole interactions, enhancing solubility and binding affinity in target-directed synthesis.
4-Amino-2-chloropyridine-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyridine-based heterocycles through palladium-catalyzed cross-coupling and electrophilic substitution reactions. Its orthogonal functional groups—amino, chloro, and carboxylic acid—support sequential transformations under mild conditions, facilitating efficient derivatization for API development. The compound exhibits good bench stability and is readily purified by recrystallization or chromatography, making it suitable for scalable synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: