Lot numbers can be found on the outside label of a product:
Please log in for operation!
*For research and further manufacturing use only, not for direct human use.
Structure of 1049730-40-6
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
This pyrazole derivative features a boronate ester group enabling efficient Suzuki-Miyaura coupling, paired with a difluoroethyl substituent that enhances metabolic stability and lipophilicity. The tetramethyl-1,3,2-dioxaborolane moiety ensures excellent shelf stability and reactivity under mild conditions.
1-(2,2-Difluoroethyl)-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables efficient coupling with aryl and heteroaryl halides under mild conditions, while the 2,2-difluoroethyl substituent enhances metabolic stability and modulates lipophilicity. This compound exhibits excellent bench stability, tolerates common functional groups, and simplifies purification—making it well-suited for iterative synthesis of complex pyrazole-based scaffolds in medicinal chemistry and process development.
|
GHS Pictogram :
|
GHS No : GHS05,GHS07
|
|
Signal Word : Danger
|
UN#: 1759
|
|
Class : 8
|
Packing Group : Ⅲ
|
|
Hazard Statements : H315-H318-H335
|
|
|
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Lot numbers can be found on the outside label of a product: