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CS-W001157 4
Total: USD 88.00

(R)-2-(Benzylamino)-3-hydroxypropanoic acid

  • CAS No. 106910-77-4

  • Cat. No. CS-0043104
  • Purity≥98%
  • MDL No.MFCD12198844

*For research and further manufacturing use only, not for direct human use.

(R)-2-(Benzylamino)-3-hydroxypropanoic acid|CS-0043104

Structure of 106910-77-4

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General Information

  • CAS No. 106910-77-4
  • Cat. No. CS-0043104
  • Purity ≥98%
  • MDL No. MFCD12198844
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃NO₃
  • Molecular Weight 195.22
  • Synonym(s) None
  • SMILES O=C(O)[C@H](NCC1=CC=CC=C1)CO

Description

(R)-2-(Benzylamino)-3-hydroxypropanoic acid features a chiral center at the C-2 position, delivering enantiomerically pure stereochemistry essential for asymmetric synthesis. The pendant hydroxyl group enables selective derivatization, while the benzylamino moiety imparts solubility and facilitates incorporation into peptidomimetic scaffolds. This compound serves as a key building block in the development of bioactive small molecules and enzyme inhibitors.

Application

(R)-2-(Benzylamino)-3-hydroxypropanoic acid serves as a key chiral building block for the synthesis of β-amino alcohol motifs found in bioactive molecules. Its well-defined stereochemistry enables reliable incorporation into peptidomimetics and kinase inhibitors. The molecule exhibits bench stability, tolerates standard protecting group manipulations, and participates in efficient coupling reactions with minimal racemization.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   69.56
  • LogP   0.2217
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   5

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