Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

tert-Butyl (3S,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate

  • CAS No. 1174020-40-6

  • Cat. No. CS-0047556
  • Purity≥97%
  • MDL No.MFCD18632748
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (3S,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate|CS-0047556

Structure of 1174020-40-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

Description

This tert-butyl (3S,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate features a stereochemically defined piperidine scaffold with fluorine and hydroxyl groups positioned for precise molecular integration. The bench-stable tert-butyl carbamate protects the amine during synthetic manipulations, enabling efficient incorporation into bioactive molecules. This configuration supports conformational rigidity in target compounds, enhancing binding affinity and metabolic stability.

Application

tert-Butyl (3S,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate serves as a stereochemically defined building block for fluorinated piperidine scaffolds. The protected hydroxyl group enables selective functionalization, while the fluorine substituent imparts metabolic stability and modulates electronic properties. This intermediate exhibits excellent bench stability and facilitates downstream transformations including coupling reactions and cyclizations, making it valuable in medicinal chemistry and API synthesis.

General Information

  • CAS No. 1174020-40-6
  • Cat. No. CS-0047556
  • Purity ≥97%
  • MDL No. MFCD18632748
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₈FNO₃
  • Molecular Weight 219.25
  • Synonym(s) (3S,4R)-tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate
  • SMILES O=C(N1C[C@H](F)[C@H](O)CC1)OC(C)(C)C

Computational Chemistry Data

  • TPSA   49.77
  • LogP   1.3262
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1174020-40-6 sigma1174020-40-6 manufacturer1174020-40-6 price1174020-40-6 structure1174020-40-6 SDSbuy 1174020-40-61174020-40-6 supplier1174020-40-6 uses1174020-40-6 molecular weightprice of 1174020-40-61174020-40-6 chemical name formula of 1174020-40-6
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label