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Structure of 117519-16-1
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2-Bromo-6-(trifluoromethyl)pyridin-3-amine features a bromine atom at the 2-position and a trifluoromethyl group at the 6-position of the pyridine ring, with an amine substituent at the 3-position. This electron-deficient heterocycle enables efficient cross-coupling reactions in medicinal chemistry. The molecule exhibits enhanced metabolic stability and lipophilicity, facilitating incorporation into bioactive scaffolds. Its bench-stable nature supports routine handling under standard conditions.
2-Bromo-6-(trifluoromethyl)pyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its reactive bromide and electron-deficient pyridine core. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the amine functionality allows for direct derivatization or incorporation into heterocyclic scaffolds. Bench-stable and compatible with standard purification methods, it facilitates efficient synthesis of advanced intermediates for pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: