(S)-3-Amino-gamma-butyrolactone hydrochloride

Name: (S)-3-Amino-gamma-butyrolactone hydrochloride
Brand: ChemScene
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CAS No. 117752-82-6
Cat. No. CS-W009169
Purity≥97%
MDL No.MFCD11114557

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(S)-3-Amino-gamma-butyrolactone hydrochloride|CS-W009169

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Description

(S)-3-Amino-gamma-butyrolactone hydrochloride is a chiral lactam derivative featuring a primary amine and a hydrolytically stable cyclic ester. This bench-stable, moisture-tolerant compound serves as a key intermediate in the synthesis of bioactive heterocycles and peptidomimetics, where its defined stereochemistry enables precise control over downstream molecular architecture.

Application

(S)-3-Amino-gamma-butyrolactone hydrochloride serves as a key chiral building block in the synthesis of bioactive heterocycles and amino acid derivatives. Its well-defined stereochemistry and stable lactone framework facilitate selective transformations, including ring-opening reactions and amine functionalization. The hydrochloride salt enhances solubility and handling stability, enabling straightforward incorporation into peptide-like scaffolds and medicinal chemistry campaigns requiring stereocontrolled nitrogen-containing motifs.

General Information

CAS No. 117752-82-6
Cat. No. CS-W009169
Purity ≥97%
MDL No. MFCD11114557
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₈ClNO₂
Molecular Weight 137.56
Synonym(s) (S)-4-aminodihydrofuran-2(3H)-one hydrochloride
SMILES O=C1OC[C@@H](N)C1.[H]Cl

Computational Chemistry Data

TPSA 52.32
LogP -0.3176
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydrofuran compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-3-Amino-gamma-butyrolactone hydrochloride

CAS No. 117752-82-6

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