Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Tos-PEG4-NH-Boc

  • CAS No. 1246999-33-6

  • Cat. No. CS-0100056
  • Purity≥97%
  • MDL No.MFCD27635161

*For research and further manufacturing use only, not for direct human use.

Tos-PEG4-NH-Boc|CS-0100056

Structure of 1246999-33-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1246999-33-6
  • Cat. No. CS-0100056
  • Purity ≥97%
  • MDL No. MFCD27635161
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₃₃NO₈S
  • Molecular Weight 447.54
  • Synonym(s) PROTAC Linker 7
  • SMILES O=C(OC(C)(C)C)NCCOCCOCCOCCOS(=O)(C1=CC=C(C)C=C1)=O

Description

Tos-PEG4-NH-Boc features a tert-butyl carbamate-protected amine linked via a four-unit polyethylene glycol spacer to a tosylated terminus. This bifunctional reagent enables site-specific conjugation in aqueous environments, combining the stability of the Boc group with the solubility and biocompatibility of PEG. Ideal for peptide derivatization and bioconjugation workflows requiring orthogonal protection and controlled release.

Application

Tos-PEG4-NH-Boc serves as a versatile bifunctional building block for peptide and oligonucleotide conjugation, enabling efficient N-terminal capping and site-specific attachment. The tosyl (Tos) group provides a robust leaving group for nucleophilic substitution, while the PEG4 spacer offers enhanced solubility and reduced aggregation. The Boc-protected amine facilitates subsequent deprotection and functionalization under standard acidic conditions. This structure enables clean, high-yielding coupling reactions with minimal side-product formation, making it ideal for modular synthesis of bioconjugates and peptidomimetics.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   109.39
  • LogP   2.27482
  • H_Acceptors   8
  • H_Donors   1
  • Rotatable_Bonds   14

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Tos-PEG4-NH-Boc sigmaTos-PEG4-NH-Boc manufacturerTos-PEG4-NH-Boc priceTos-PEG4-NH-Boc structureTos-PEG4-NH-Boc SDSbuy Tos-PEG4-NH-BocTos-PEG4-NH-Boc supplierTos-PEG4-NH-Boc usesTos-PEG4-NH-Boc molecular weightprice of Tos-PEG4-NH-BocTos-PEG4-NH-Boc chemical name formula of Tos-PEG4-NH-Boc
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label