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Structure of 1268883-21-1
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This trifluoromethyl-substituted oxetane features a stable, electron-deficient heterocyclic core that enhances metabolic resistance and membrane permeability. The amine functionality, delivered as the hydrochloride salt, enables straightforward conjugation and solubility in aqueous systems. Designed for use in medicinal chemistry, this compound integrates readily into bioactive scaffolds to improve pharmacokinetic profiles through enhanced stability and lipophilicity balance.
3-(Trifluoromethyl)oxetan-3-amine hydrochloride serves as a valuable building block for medicinal chemistry, enabling the incorporation of a polar, metabolically stable trifluoromethyl-substituted oxetane moiety. Its amine functionality facilitates straightforward derivatization via amidation, alkylation, or reductive amination, while the hydrochloride salt ensures excellent bench stability and ease of handling. The trifluoromethyl group enhances lipophilicity and bioavailability, making it particularly useful in constructing advanced API scaffolds with improved pharmacokinetic profiles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: