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CS-W001157 4
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2-(4-Bromophenyl)cyclopropanamine hydrochloride

  • CAS No. 1306604-68-1

  • Cat. No. CS-0157595
  • Purity≥90%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(4-Bromophenyl)cyclopropanamine hydrochloride|CS-0157595

Structure of 1306604-68-1

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General Information

  • CAS No. 1306604-68-1
  • Cat. No. CS-0157595
  • Purity ≥90%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁BrClN
  • Molecular Weight 248.55
  • Synonym(s) 2-(4-Bromophenyl)cyclopropan-1-amine hydrochloride
  • SMILES BrC1=CC=C(C2CC2N)C=C1.Cl

Description

This cyclopropanamine hydrochloride features a 4-bromophenyl substituent that imparts electron-withdrawing character and enhances metabolic stability. The strained cyclopropyl ring enables unique conformational rigidity, while the protonated amine ensures solubility and facilitates salt formation. Ideal for medicinal chemistry applications requiring bioisosteric replacement or targeted receptor engagement.

Application

2-(4-Bromophenyl)cyclopropanamine hydrochloride serves as a valuable building block in medicinal chemistry, enabling the synthesis of bioactive cyclopropyl-containing arylamines. Its stable hydrochloride salt form enhances handling and purification, while the bromoaryl group facilitates subsequent cross-coupling reactions. The cyclopropane ring imparts conformational rigidity, offering structural control in target molecule design. This compound functions effectively in standard amine-based transformations and is compatible with common reaction conditions used in pharmaceutical development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.6855
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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